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Check for signs of urinary retention or minimized gastric motility if oliceridine is coadministered with anticholinergics.enasidenib will improve the stage or influence of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Check. Enasidenib (a weak CYP2C19 inhibitor) may well improve systemic exposure of delicate CYP2C19 substrate